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NEW QUESTION: 1
A Hispanic client brings her father to the clinic because he is becoming more forgetful. He is diagnosed with Alzheimer's disease. The woman tells the nurse that she wants to try ginkgo biloba for her father, before using prescription medications. Which of the following is an appropriate response by the nurse?
A. "It is wiser to start a prescription."
B. "That herb won't do your father any good."
C. "You can't expect an herb to treat Alzheimer's."
D. "I will let the physician know of your wishes."
Answer: D
Explanation:
The culturally sensitive response is to notify the physician of the family member's wishes and to determine whether it is feasible. Ginkgo biloba has been shown to be of some benefit in treating dementia. The other statements are not culturally sensitive.Reduction of Risk Potential
NEW QUESTION: 2
Which of the following statements is true regarding Drug-receptor bonds?
A. Covalent bonds of drugs with receptors are strong and mostly reversible
B. Electrostatic bonds are stronger than covalent bonds
C. Hydrophobic bonds are weak bonds and they are important in the interactions of highly water soluble drugs with the lipids of cell membranes
D. Bond formation of between the acetyl group of aspirin and cyclo-oxygenase enzyme is a covalent bond
E. Covalent bonding is much more common than electrostatic bonding in drug-receptor interactions
Answer: D
Explanation:
Explanation
Drugs mainly interact with the receptors by means of chemical forces or bonds. There are three major types of drug receptor bonds: - Covalent - Electrostatic - Hydrophobic Covalent bonds are very strong bonds and in most of the cases they are irreversible under biologic conditions. For example, the covalent bond between the acetyl group of aspirin and cyclo-oxygenase enzyme (target enzyme present on the platelets) does not breaks easily. The platelet aggregation effect of aspirin lasts long after free acetyl-salicylic acid has disappeared from the blood (about 15 minutes) and it is reversed only by the synthesis of new cyclo-oxygenase enzyme in new platelets which takes a long time. Hence the effect of aspirin is seen after the drug is stopped. Among the drug receptor interactions, electrostatic bond is much more commonly found than covalent bond. The electrostatic bonds vary from relatively strong linkages between permanently charged ionic molecules to weaker hydrogen bonds and very weak induced dipole interactions such as van der Waals force. The electrostatic bonds are weaker than covalent bonds. Hydrophobic bonds are usually very weak bonds and probably important in the interactions of highly lipid soluble drugs with the lipids of cell membranes and perhaps in the interactions of the drugs with the internal walls of receptor "pockets".
NEW QUESTION: 3
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E. 顧客に代わってリクエストを作成する
Answer: C,E
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